Founded in 1877 in Peoria, Illinois by Bishop Spalding and Mother M. Frances Krasse, the Sisters of the Third Order of St. Francis strive to follow the Gospel, particularly in the care of the sick and the poor. Because Christ is the center of their lives, a deep prayer life is fostered and is the foundation from which their apostolic works flow.

Healthcare and education are the community's main apostolate. They have medical centers, hospitals, colleges of nursing, and a nursing home in Illinois and Michigan.

Entrance requirements include: a desire to serve the Lord, a generous spirit, good mental and physical health, and skills to be a joyful Franciscan in community.